fiveyearswasted wrote:If you think about what a strep infection does (at least the stuff that we know about).....through molecular mimicry it copies the cell walls of of the cells around it and confuses the immune system initiating an auto-immune attack of the immune system against your own body. This is why simple strep infections turn into serious stuff like rheumatic fever: http://en.wikipedia.org/wiki/Rheumatic_fever
where the immune system is turned against the heart and or brain.
It is short sighted to not test ASO, D-Nase, and ANA levels to determine if there is / was a strep infection, and an ongoing autoimmune response. Visual ticks should be secondary or considered separately from testing. Positive tests are 100% conclusive of an infection.
FWIW, my son had elevated levels of the 3 tests mentioned.
Modern examples have shown us that there are plenty of kids with negative test results that quite clearly do have PANDAS. That is where the visual signs (ticks, movement & speech issues) can warrant the empirical use of antibiotics. Ticks do not mean that testing should be skipped, instead it means that testing is all the more important.
Our immunologist, who specializes in PANDAS, refused to order those blood tests. Here is his reply I got today: "The ASO and DnAse antibody tests would be helpful if this was acute not chronic. I find nothing to suggest an autoimmune component to his diease course and nothing to suggest PANDAS. I would not suggest further labs or any immune suppressant therapy."