CRISPR and biohacking

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FatherOf2
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CRISPR and biohacking

Postby FatherOf2 » Mon Nov 20, 2017 2:22 am

Biohacking started much sooner than I expected:http://www.cbc.ca/radio/quirks/diy-dna-hacks-wounds-take-longer-to-heal-at-night-why-daydreams-are-good-quirks-bombs-and-more-1.4395576/meet-the-human-guinea-pig-who-hacked-his-own-dna-1.4395589 This field is going to explode. FDA has been trying to impose the same requirements on gene editing as any new drug development: 3 stages of clinical studies followed by FDA approval. Currently there are just a few companies working on gene editing:

Bluebird Bio (sickle cell anemia)
Sarepta Therapeutics (Duchenne Muscular Dystrophy)
Biomarin (hemophilia A)
Spark Therapeutics (biallelic RPE65-mediated inherited retinal disease) - FDA approved this year

These treatments will cost close to $1mln/year. However, biohacking could be a parallel faster and cheaper path but full of unpredictable results including tragedies. I can see how people with SNP mutations responsible for such developmental disorders as Rett and Fragile X will join the ranks of biohacking instead of waiting for some company to start developing a gene editing therapy through regular FDA channels, which may take 7 years - the time that we don't have. Even people with non-debilitating disorders such as boldness but with enough money soon will be practicing biohacking.

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