Transcranial DC stimulation in ASD: double blind cross study

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Transcranial DC stimulation in ASD: double blind cross study

Postby kulkulkan » Wed Jan 14, 2015 6:00 pm

Using direct current stimulation (tDCS), not rTMS. Small study (n=20) but found statistically significant results (double blinded) within 5-7 days, which is impressive.

Full study here

Behav Neurol. 2014;2014:173073. doi: 10.1155/2014/173073. Epub 2014 Oct 30.
Effect of anodal transcranial direct current stimulation on autism: a randomized double-blind crossover trial.
Amatachaya A1, Auvichayapat N2, Patjanasoontorn N3, Suphakunpinyo C2, Ngernyam N1, Aree-Uea B1, Keeratitanont K1, Auvichayapat P1.
Author information
The aim of this study was to evaluate the Childhood Autism Rating Scale (CARS), Autism Treatment Evaluation Checklist (ATEC), and Children's Global Assessment Scale (CGAS) after anodal transcranial direct current stimulation (tDCS) in individuals with autism. Twenty patients with autism received 5 consecutive days of both sham and active tDCS stimulation (1 mA) in a randomized double-blind crossover trial over the left dorsolateral prefrontal cortex (F3) for 20 minutes in different orders. Measures of CARS, ATEC, and CGAS were administered before treatment and at 7 days posttreatment. The result showed statistical decrease in CARS score (P < 0.001). ATEC total was decreased from 67.25 to 58 (P < 0.001). CGAS was increased at 7 days posttreatment (P = 0.042). Our study suggests that anodal tDCS over the F3 may be a useful clinical tool in autism.

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