Impaired recycling of mitochondria in autism?

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AspieGenes
Posts: 114
Joined: Wed Sep 28, 2016 12:32 pm

Impaired recycling of mitochondria in autism?

Postby AspieGenes » Sun Oct 23, 2016 1:34 pm

Of course it is about the mitiochondria, which is why it affects boys more than girls. (mtDNA) Sulfite Oxidase (SUOX) is one of these.


https://www.sciencedaily.com/releases/2016/10/161018143307.htm

Impaired recycling of mitochondria in autism?

Tuberous sclerosis complex (TSC), a genetic disorder that causes autism in about half of those affected, could stem from a defect in a basic system cells use to recycle their mitochondria, report scientists at Boston Children's Hospital. The scientists believe their findings, published online October 18 by Cell Reports, open new treatment possibilities not just for TSC, but possibly for other forms of autism and some neurologic disorders.

Mitochondria, the organelles responsible for cellular energy production and metabolism, constantly get recycled. Through a process known as autophagy ("self-eating"), cells literally digest their damaged or aging mitochondria, clearing the way for healthy replacements.

AspieGenes
Posts: 114
Joined: Wed Sep 28, 2016 12:32 pm

Re: Impaired recycling of mitochondria in autism?

Postby AspieGenes » Sun Oct 23, 2016 1:52 pm

http://mitochondrialdiseasenews.com/201 ... mutations/

Unlike the nuclear genetic material that comes from both our father and mother, the mitochondrial genome is inherited exclusively from our mother. Researchers at the Fred Hutchinson Cancer Research Center have shown for the first time that this may lead to mutations in the mitochondrial DNA (mtDNA) that are harmful to a women’s sons but not to their daughters, a phenomenon known as “mother’s curse.”


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